

The Sequence differs also in structure and melody from the hymn for whilst all the strophes of a hymn are always constructed according to the same metre and rhythm and are sung to the same melody as the first strophe, it is the peculiarity of the Sequence, due to its origin, that (at least in those of the first epoch) each strophe or pair of strophes is constructed on a different plan. The Sequence ( Sequentia)-or, more accurately as will be seen further on, the Prose ( Prosa)-is the liturgical hymn of the Mass, in which it occurs on festivals between the Gradual and the Gospel, while the hymn, properly so called, belongs to the Breviary. Includes the Catholic Encyclopedia, Church Fathers, Summa, Bible and more all for only $19.99. Ruiqiang Li, Yingrui Li, Hancheng Zheng and Ruibang Luo: These authors contributed equally to this work.Please help support the mission of New Advent and get the full contents of this website as an instant download. Inference of population structure using multilocus genotype data: dominant markers and null alleles. Extensive copy-number variation of the human olfactory receptor gene family. Structural classification of zinc fingers: survey and summary. Classification and nomenclature of all human homeobox genes. Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements. A population threshold for functional polymorphisms. The first Korean genome sequence and analysis: full genome sequencing for a socio-ethnic group. Characterization of single-nucleotide polymorphisms in coding regions of human genes. Use of y chromosome and mitochondrial DNA population structure in tracing human migrations. Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genotype, haplotype and copy-number variation in worldwide human populations. Worldwide human relationships inferred from genome-wide patterns of variation. Genetic variation and population structure in native Americans. The genetic structure and history of Africans and African Americans.

The Human Genome Diversity Project: past, present and future. A human genome diversity cell line panel. Closing gaps in the human genome with fosmid resources generated from multiple individuals.

De novo assembly of the human genomes with massively parallel short read sequencing. Accurate whole human genome sequencing using reversible terminator chemistry. The diploid genome sequence of an Asian individual. The complete genome of an individual by massively parallel DNA sequencing. The diploid genome sequence of an individual human. Detection of large-scale variation in the human genome. Large-scale copy number polymorphism in the human genome. Mapping and sequencing of structural variation from eight human genomes. Genome assembly comparison identifies structural variants in the human genome. Genome-wide association studies for common diseases and complex traits. Whole-genome patterns of common DNA variation in three human populations. A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Human genetic variation and its contribution to complex traits. Finishing the euchromatic sequence of the human genome. International Human Genome Sequencing Consortium.

The extensive amount of novel sequence contributing to the genetic variation of the pan-genome indicates the importance of using complete genome sequencing and de novo assembly. We estimate that a complete human pan-genome would contain ∼19–40 Mb of novel sequence not present in the extant reference genome. Cross-species conservation analysis of predicted genes indicated that the novel sequences contain potentially functional coding regions. We found novel sequences present in patterns consistent with known human migration paths. Most novel sequences are individual or population specific, as revealed by their comparison to all available human DNA sequence and by PCR validation using the human genome diversity cell line panel. We identified ∼5 Mb of novel sequences not present in the reference genome in each of these assemblies. Here we integrate the de novo assembly of an Asian and an African genome with the NCBI reference human genome, as a step toward constructing the human pan-genome.
